Novacort combines 2% hydrocortisone acetate (an anti-inflammatory) and 1% pramoxine hydrochloride (a topical anesthetic) in a proprietary biopeptide aloe complex delivery vehicle.
Novacort is an easy-to-distribute prescription gel to provide relief of the inflammation, pain and pruritus (itching) of dermatitis and hemorrhoids. Novacort is fragrance free, dye free and paraben-free for low irritation.
By combining a topical anesthetic (pramoxine) with the anti-inflammatory hydrocortisone, Novacort provides relief of dermatitis and hemorrhoids plus:
- Enhanced comfort from the added topical anesthetic
- Help breaking the "itch-scratch" cycle to prevent complications
- It may help reduce the need for higher-potency steroids
- Only your doctor can weigh the risks and benefits and decide if Novacort is right for you
Novacort is suitable for inflammatory conditions such as dermatitis and also internal and external hemorrhoids, peri-anal itching and anal fissures. Each box contains a special applicator for use when treating internal hemorrhoids.
When compared to other topical prescription products, Novacort offers a number of significant benefits:
Warnings and Precautions
The following warnings and precautions should be kept in mind when using Novacort (and in most cases, when using other hydrocortisone-containing products):
- Novacort is contraindicated for people who have hypersensitivity to hydrocortisone or pramoxine.
- In some patients, systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression and other conditions.
- Avoid prolonged use over large surface areas, especially with occlusive dressings.
- Burning, itching, irritation and dryness have been reported infrequently following the use of topical corticosteroids.
Novacort is to be used as directed by your physician, only for the condition for which it was prescribed. Avoid contact with eyes. Treated skin should not be bandaged or otherwise covered or wrapped unless directed by the physician. Report any signs of local adverse reactions. Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area.
Hydrocortisone has a history of many decades of safe and effective use for inflammatory skin conditions and numerous clinical studies are available documenting its performance on the Internet.
Pramoxine hydrochloride (HCl) also has been well-documented to provide beneficial topical anesthetic effects with a low incidence of sensitivity or reactions. In one such published study(1), pramoxine HCl was shown to perform significantly better than placebo on the following measures:
- 93% of patients treated with pramoxine HCl experienced itch reduction versus 36% for those treated by placebo;
- Itch duration was reduced by 71% among those given pramoxine HCl;
- Pramoxine HCl was fast-acting, with an onset of action of 2-6 minutes; and
- Pramoxine was long-lasting, lasting several hours for most patients. (2)